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Effect of water-soluble reduced chitosan on volatile sulfur compounds

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¹è±¤ÇР( Bae Kwang-Hak ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ¿¹¹æÄ¡Çб³½Ç
ÇÏÁ¤Àº ( Ha Jung-Eun ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ¿¹¹æÄ¡Çб³½Ç
ÀüÀºÁÖ ( Jun Eun-Joo ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¿¹¹æÄ¡°úÇб³½Ç
Çѵ¿Çå ( Han Dong-Hun ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¿¹¹æÄ¡°úÇб³½Ç
¹é´ëÀÏ ( Paik Dai-Il ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ¿¹¹æÄ¡Çб³½Ç
±èÁø¹ü ( Kim Jin-Bom ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¿¹¹æÄ¡°úÇб³½Ç

Abstract


Objectives: This study examined the effects of newly developed water-soluble reduced chitosan on the volatile sulfur compounds induced by 4-day plaque regrowth.

Methods: 1.0% water-soluble reduced chitosan with a pH ranging from 6.0 to 6.5, a molecular weight between 3,000 and 5,000 Da, and a 70% of degree of deacetylation was used. The amounts of volatile sulfur compounds in the mouth air were measured in vivo. Twelve dental students volunteered to participate in this double blind, randomized, 4-day plaque regrowth study. The subjects were divided into three groups and asked to rinse with the allocated mouthrinse solution and refraining from all mechanical oral hygiene measures.

Results: The chitosan mouthwash reduced significantly the amounts of hydrogen sulfide in the mouth air compared to DW.

Conclusions: The water-soluble reduced chitosan exhibited significant malodor-reducing activity during the 4-day plaque regrowth experiment.

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oral malodor;volatile sulfur compounds;water-soluble reduced chitosan

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KoreaMed